Medication Adherence in Type 2 Diabetes Mellitus Patients with Diabetic Ulcer: Systematic Literature Review
English
DOI:
https://doi.org/10.55392/indarcbiores.v1i2.13Keywords:
medication adherence, type 2 diabetes mellitus, diabetic ulcerAbstract
Background: Patient non-adherence to diabetes medication can worsen the patient's condition and increase the risk of diabetes complications such as diabetic ulcers. A sufficient level of medication adherence can prevent diabetic complications. This study aimed to determine the level of medication adherence of type 2 DM patients with diabetic ulcers.
Review: This research uses a systematic literature review with a PRISMA chart as a research design guideline. Researchers searched three databases, namely PubMed, Google Scholar, and ScienceDirect, using predefined keywords. The search resulted in 2,763 literatures then 11 literatures that met the criteria were taken. The number of respondents obtained amounted to 1,082 people. Characteristics of type 2 DM patients with diabetic ulcers: respondents were female, aged under 60 years, had diabetes for more than five years, used oral medication, insulin, or combination, could have normal or excess BMI, and possibly had hypertension or neuropathy. The result from systematic literature review obtained seven pieces of literature that had a low medication adherence level, two pieces of literature showed no correlation between medication adherence and the incidence of diabetic ulcers in type 2 DM patients, and two pieces of literature had a sufficient level of medication adherence.
Summary: The level of medication adherence in type 2 DM patients with diabetic ulcers varies. However, more literature contains results in low medication adherence of type 2 Diabetes Mellitus patients with diabetic ulcers, so it needs to be improved in the future.
Keywords: diabetic ulcer, medication adherence, type 2 diabetes mellitus
Downloads
References
WHO, “Classification of diabetes mellitus,” 2019, Accessed: Dec. 21, 2021. [Online]. Available: https://apps.who.int/iris/handle/10665/325182?locale-attribute=ar&utm_source=transaction&utm_medium=email.
PERKENI, “Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia,” 2021.
ADA, “Introduction: Standards of Medical Care in Diabetes—2020,” Diabetes Care, vol. 43, no. Supplement 1, pp. S1–S2, Jan. 2020, doi: 10.2337/dc20-Sint.
S. Papadakis, M., McPhee, Current medical diagnosis and treatment, vol. 5th ed. 2015.
K. Alexiadou and J. Doupis, “Management of diabetic foot ulcers,” Diabetes Ther., vol. 3, no. 1, pp. 1–15, Dec. 2012, doi: 10.1007/S13300-012-0004-9/FIGURES/2.
M. Wildan, S. Wibisono, and H. Soebroto, “Correlation Between The History of Previous Lower Extremity Amputation as a Risk Factor for the Subsequent Lower Extremity Amputation in Diabetic Patients Among RSUD Dr. Soetomo Patients in 2018,” Heal. Notions, vol. 4, no. 10, pp. 349–352, Oct. 2020, doi: 10.33846/HN41008.
A. S. Hariftyani, “Faktor Risiko Kematian Pada Pasien Dengan Ulkus Kaki Diabetik Di RSUD Dr. Soetomo Periode 2016-2018,” 2020, Accessed: Dec. 21, 2021. [Online]. Available: http://repository.unair.ac.id/103909/.
O. Nanda, B. Wiryanto, and E. A. Triyono, “Hubungan kepatuhan minum obat anti diabetik dengan regulasi kadar gula darah pada pasien perempuan diabetes mellitus,” Amerta Nutr., pp. 2(4), 340–348, 2018, doi: 10.2473/amnt.v2i4.2018.340-348.
A. Rahmawati, “Pengaruh Keteraturan Berobat dan Aktivitas Fisik Terhadap Kejadian Neuropati Diabetik Tipe 2,” J. Wiyata Penelit. Sains dan Kesehat., vol. 6, no. 2, pp. 80–87, Jan. 2020, Accessed: Oct. 19, 2021. [Online]. Available: https://www.wiyata.iik.ac.id/index.php/wiyata/article/view/175.
H. Nursalam, “Penulisan Literature Review dan Systematic Review Pada Pendidikan Kesehatan (Contoh),” academia.edu, 2020, Accessed: Dec. 21, 2021. [Online]. Available: https://www.academia.edu/download/63640863/16.06.2020_-_LR_SR-PendKes-contoh-final20200615-70952-smkrhg.pdf.
A. El-Awaisi, S. Joseph, M. El Hajj, L. D.-R. in S. and, and undefined 2018, “A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice,” Elsevier, 2017, doi: 10.1016/j.sapharm.2017.11.001.
A. Marselin, F. Agung, D. Hartanto, M. Putri, and S. Utami, “Kepatuhan Minum Obat Pada Pasien Ulkus Diabetikum Di Propinsi Daerah Istimewa Yogyakarta: Mix Method,” J. Ilm. Farm. Farmasyifa, vol. 4, no. 2, pp. 51–58, Aug. 2021, doi: 10.29313/jiff.v4i2.7961.
S. Hermoyowati, “Gambaran Tingkat Kepatuhan Minum Obat dan Diet Makan Pasien Diabetes Melitus dengan Ulkus Kaki di Perawatan Luka Wecare,” 2020, Accessed: Dec. 21, 2021. [Online]. Available: http://librepo.stikesnas.ac.id/69/.
S. D. Megayanti and N. P. I. Suantika, S.Kep., M.Kep, “Self Care pada Pasien Diabetes Melitus dengan Penyulit Ulkus Kaki Diabetik,” ojs.itekes-bali.ac.id, 2021, Accessed: Dec. 21, 2021. [Online]. Available: http://ojs.itekes-bali.ac.id/index.php/jrkn/article/view/306.
A. N. Ikeri, “Monitoring Patient and Caregiver Adherence to Treatment in Management of Vascular Ulcers,” 2020, Accessed: Dec. 21, 2021. [Online]. Available: https://idun.augsburg.edu/etd/1031/.
R. Natovich, I. Harman-Boehm, D. Margalit, T. Cukierman-Yaffe, and T. Kushnir, “Adherence to self-care among individuals with diabetes with and without diabetic foot complications: objective and self-report measures,” Diabetes Manag., vol. 7, no. 2, pp. 234-, 2017, Accessed: Dec. 21, 2021. [Online]. Available: https://www.openaccessjournals.com/articles/adherence-to-selfcare-among-individuals-with-diabetes-with-and-without-diabetic-foot-complications-objective-and-selfreport-measur.html.
C. Nwaukwa, “Predictive Relationship between Treatment Adherence Glycated Hemoglobin and Diabetic Complications among Jamaicans,” 2018, Accessed: Dec. 21, 2021. [Online]. Available: https://search.proquest.com/openview/07e5d75d63315e0c608e7309210e0dee/1?pq-origsite=gscholar&cbl=18750.
I. Mustafa, “Determinan Epidemiologis Kejadian Ulkus Kaki Diabetik Pada Penderita Diabetes Mellitus Di Rsud Dr. Chasan Boesoirie Dan Diabetes Center Ternate,” 2016, Accessed: Dec. 21, 2021. [Online]. Available: http://repository.unair.ac.id/53837/.
A. Afroz et al., “Macro-and micro-vascular complications and their determinants among people with type 2 diabetes in Bangladesh,” Elsevier, 2019, doi: 10.1016/j.dsx.2019.07.046.
S. Galal, K. Al-Ali, N. Sharaf, M. El-Baz, and K. T. El-Din, “Does the Acquirement of Knowledge Prevent Diabetes-Related Foot Problems?,” J. Healthc. Commun., pp. 1(2), 10., 2016, Accessed: Dec. 21, 2021. [Online]. Available: https://www.eartbreak.com/healthcare-communications/does-the-acquirement-of-knowledge-prevent-diabetes-related-foot-problems.pdf.
H. Tjahjono, “Self Management Diabetes pada Pasien Diabetes Melitus Dengan Ulkus Diabetikum di Puskesmas Jagir Surabaya,” jurnal.stikeswilliambooth.ac.id, 2020, Accessed: Dec. 22, 2021. [Online]. Available: http://jurnal.stikeswilliambooth.ac.id/index.php/Kep/article/view/212.
M. Khan, U. Azhar, F. Zubair, and Z. A. Khan, “Can we link foot ulcer with risk factors in diabetics? A study in a tertiary care hospital,” Pakistan J. Med., 2018, Accessed: Dec. 21, 2021. [Online]. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6290204/.
Cristanti, “Kepatuhan Diet Dan Minum Obat Dengan Kejadian Neuropati Pada Diabetes Melitus Tipe 2,” 2017.
R. Alfian, “Korelasi Antara Kepatuhan Minum Obat dengan Kadar Gula Darah pada Pasien Diabetes Melitus Rawat Jalan di RSUD Dr. H. Moch. Ansari Saleh Banjarmasin,” ppjp.ulm.ac.id, vol. 2, no. 2, pp. 15–23, 2015, Accessed: Dec. 21, 2021. [Online]. Available: https://ppjp.ulm.ac.id/journal/index.php/pharmascience/article/view/5818.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2021 Indonesian Archives of Biomedical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
