Biofilm forming potential of Streptococcus suis: focusing on luxs/ai-2-mediated quorum sensing system

Authors

  • Tjokorda Istri Pramitasuri Doctoral Program of Medical Sciences, Faculty of Medicine, Universitas Udayana, Bali, 80232,
  • Ni Made Adi Tarini Department of Microbiology, Faculty of Medicine-Rumah Sakit Umum Pusat Sanglah, Bali, 80232,
  • Ni Made Susilawathi Department of Neurology, Faculty of Medicine-Rumah Sakit Universitas Udayana, Bali, 80361, Indonesia
  • Anak Agung Raka Sudewi Department of Neurology, Faculty of Medicine-Rumah Sakit Universitas Udayana, Bali, 80361, Indonesia

DOI:

https://doi.org/10.55392/indarcbiores.v1i1.6

Keywords:

Streptococcus suis, biofilm, Quorum Sensing, LuxS, Auto Inducer-2

Abstract

Because of its virulence and ability to survive, the incidence of infection caused by Streptococcus suis (S. suis), an emerging zoonotic pathogen, is expected to increase significantly. A biofilm-forming process, which is a cornerstone of chronic infection, influences the survival rate of S. suis. The mechanism helps bacteria to live longer in host tissues, form colonies, escape immune clearance, and share genetic information. At this moment, the most studied regulatory mechanism of S. suis biofilm formation is Quorum Sensing (QS), mainly on LuxS/AI-2-mediated QS system, in which AI-2 is the most closely related molecule to biofilm formation. In this system, LuxS acts as the key player in the process. The understanding of biofilm formation in S. suis, especially the LuxS/AI-2-mediated QS system, is a valuable contribution to future therapeutic research frameworks.

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Published

2021-06-21

How to Cite

Pramitasuri, T. I. ., Tarini, N. M. A. ., Susilawathi, N. M. ., & Raka Sudewi, A. A. (2021). Biofilm forming potential of Streptococcus suis: focusing on luxs/ai-2-mediated quorum sensing system. Indonesian Archives of Biomedical Research, 1(1), 41–46. https://doi.org/10.55392/indarcbiores.v1i1.6

Issue

Vol. 1 No. 1 (2021): Indonesian Archives of Biomedical Research (InABR). 1(1): 2021

Section

Peer-reviewed Article

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Copyright (c) 2021 Indonesian Archives of Biomedical Research

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